Amphetamine-Type Stimulants (ATS)
Alias: Amfetamine
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Interpretation
- The presence of ATS >LOQ indicates exposure within a 2- to 3-day interval preceding specimen collection.
Metabolites
- Methamphetamine is metabolized to amphetamine; both can be present in urine after methamphetamine use.
Methamphetamine → Amphetamine
- Selegiline, femprofazone, and benzphetamine are all metabolized to methamphetamine and amphetamine.
- Clobenzorex is metabolized to amphetamine.
- Amphetamine is not metabolized to methamphetamine; absence of methamphetamine in the presence of amphetamine indicates the primary drug of use is amphetamine.
- 3,4-Methylenedioxymethamphetamine (Ecstasy, MDMA) is metabolized to 3,4-methylenedioxyamphetamine (MDA).
3,4-Methylenedioxymethamphetamine → 3,4-methylenedioxy-amphetamine
Confirmation Tests:
Approximate Detection Times
| Amphetamine-Type Stimulants |
LOQ (ng/mL) |
Detection Time* up to |
| Amphetamine |
25 |
3 days |
| Methamphetamine |
25 |
3 days |
| 3,4‑Methylenedioxyamphetamine (MDA) |
25 |
2 days |
| 3,4‑Methylenedioxymethamphetamine (MDMA) |
25 |
2 days |
| Phentermine |
25 |
|
| Ephedrine/pseudoephedrine |
25 |
5 days |
*These are approximate detection times for the drug or metabolites in urine. The actual detection time depends on dose, frequency of
use, and individual metabolism.
Note: These tests do not differentiate between dextro (+) amphetamines (eg, dexamphetamine) and racemic
mixtures of dextro (+) and levo (-) isomers that are present in “street” amphetamines. These tests do not
differentiate between ephedrine and pseudoephedrine.
