Test Catalog

Test Id : FSOMA

Somatostatin (Somatotropin Release-Inhibiting Factor, SRIF)

Method Name
A short description of the method used to perform the test

Direct Radioimmunoassay (RIA)

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Somatostatin (Plasma)

Lists additional common names for a test, as an aid in searching


Somatotropin Release-Inhibiting Factor



Specimen Type
Describes the specimen type validated for testing

GI Plasma

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Patient preparation:

 1. Patient should be fasting 10-12 hours prior to collection.

 2. Patient should not be on any medications that affect insulin secretion or intestinal motility, if possible for at least 48 hours prior to collection.

Specimen Type: Plasma

Container/Tube: EDTA tube containing GI preservative: EDTAGI

Specimen Volume: 1 mL

Collection Instructions: Collect 10 mL of blood in special tube containing G.I. Preservative (T125). Specimen should be separated immediately and send 3 mL plasma frozen as soon as possible.

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

1 mL

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

Hemolysis Mild reject; Gross reject
Lipemia Mild reject; Gross reject
Icterus NA
Other Specimens other than Plasma collected in GI preservative (T125). Test is strict frozen

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
GI Plasma Frozen 90 days

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Somatostatin is a cyclic peptide originally isolated from sheep hypothalami and shown to inhibit the release of Growth Hormone. Somatostatin is present primarily in three main forms: a 14 amino acid peptide, a 28 amino acid peptide (“Big” Somatostatin), and a 12,000 molecular weight ProSomatostatin. This assay measures only the 14 amino acid form of Somatostatin. All three forms of Somatostatin have similar biological properties and overall potencies. Somatostatin is a physiological regulator of islet cell and gastrointestinal functions, and is a suppressor of many pituitary hormones including Growth Hormone, Prolactin, and Thyrotropin (TSH). Somatostatin levels are often elevated in diabetics, but the levels return to normal upon correction of the hormonal and metabolic deficiencies present. In many cases of APUDomas including VIPoma, Insulinoma, Glucagonoma, and Gastrinoma, elevated levels of Somatostatin are found. 

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Up to 25 pg/mL

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information


Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Friday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

7 to 11 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Inter Science Institute

Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test was developed and its performance characteristics determined by Inter Science Institute. It has not been cleared or approved by the US Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary.


CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.


LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

Test Id Test Order Name Order LOINC Value
FSOMA Somatostatin (Plasma) 2961-1
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
Z0933 Somatostatin, (Plasma) 2961-1

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports