Test Catalog

Test Id : CGBS

Group B Streptococcus (Streptococcus agalactiae) Culture, Varies

Useful For
Suggests clinical disorders or settings where the test may be helpful

Screening for maternal colonization with Streptococcus agalactiae at 36 to 37 weeks gestation as a guide for intrapartum antibiotic prophylaxis to decrease the risk of infection by S agalactiae (group B streptococcus) in the infant

Highlights

This test is utilized to assess for the presence of Streptococcus agalactiae (group B streptococcus) in pregnant women.

Reflex Tests
Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test Id Reporting Name Available Separately Always Performed
RMALD Ident by MALDI-TOF mass spec No, Bill Only No
GID Bacteria Identification No, Bill Only No
STRP Identification Streptococcus No, Bill Only No
ISAE Aerobe Ident by Sequencing No, Bill Only No
SIDC Ident Serologic Agglut Method 4 No, Bill Only No

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, the reflex tests may be performed and charged.

Method Name
A short description of the method used to perform the test

Conventional Culture Technique

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Grp B Strep (S. agalactiae) Culture

Aliases
Lists additional common names for a test, as an aid in searching

87346-CGBS

Beta-Hemolytic Strep

Strep Group B

Group B streptococcus

Group B streptococci

S. agalactiae

Streptococcus agalactiae

Beta Strep

SGB

GBS

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, the reflex tests may be performed and charged.

Specimen Type
Describes the specimen type validated for testing

Varies

Shipping Instructions

Specimen must arrive within 24 hours of collection.

Necessary Information

Specimen source is required.

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Supplies: Culturette (BBL Culture Swab) (T092)

Specimen Type: Swab

Sources: Vaginal/rectal combination swab

Container/Tube: Culture transport swab (Dacron or rayon swab with aluminum or plastic shaft with either Stuart or Amies liquid medium)

Specimen Volume: Swab

Additional Information:

Vaginal/rectal combination swab is the only acceptable specimen according to American College of Obstetricians and Gynecologists (ACOG) guidelines. Vaginal only,  rectal only, as well as other sources are not acceptable.

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

Other Dry swab

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Varies Ambient (preferred) 24 hours
Refrigerated 24 hours

Useful For
Suggests clinical disorders or settings where the test may be helpful

Screening for maternal colonization with Streptococcus agalactiae at 36 to 37 weeks gestation as a guide for intrapartum antibiotic prophylaxis to decrease the risk of infection by S agalactiae (group B streptococcus) in the infant

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, the reflex tests may be performed and charged.

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Streptococcus agalactiae (group B streptococcus) is a cause of morbidity and mortality among infants. Infections occurring within the first week of life are considered early-onset; those occurring in infants greater than 1 week of age are considered late-onset. Maternal vaginal or rectal colonization with S agalactiae is a risk factor for early-onset disease in infants. Ten to 30% of pregnant women are vaginally or rectally colonized with S agalactiae and may transmit the organism to their infant during labor and delivery. The American College of Obstetricians and Gynecologists recommends screening for colonization with S agalactiae at 36 to 37 weeks gestation as a guide for intrapartum antibiotic prophylaxis to decrease the risk of infection with Streptococcus agalactiae in the infant.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Negative

Interpretation
Provides information to assist in interpretation of the test results

Positive cultures are reported out as Streptococcus agalactiae.

Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

No significant cautionary statements

Clinical Reference
Recommendations for in-depth reading of a clinical nature

Prevention of Group B Streptococcal Early-Onset Disease in Newborns: American College of Obstetricians and Gynecologists Committee Opinion. July 2019;(134):1. https://www.acog.org/Clinical-Guidance-and-Publications/Committee-Opinions/Committee-on-Obstetric-Practice/Prevention-of-Group-B-Streptococcal-Early-Onset-Disease-in-Newborns

Method Description
Describes how the test is performed and provides a method-specific reference

Swabs are cultured to a sheep blood agar plate, a Columbia colistin-nalidixic acid agar plate, and a LIM broth. Cultures are incubated for 2 to 3 days, depending on microbial growth present. Streptococcus agalactiae is identified using one or a combination of the following techniques: matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry, conventional biochemical tests, latex antigen test, and nucleic acid sequencing of the 16S ribosomal RNA (rRNA) gene. Streptococcus agalactiae or no growth of S agalactiae is reported.(Church DL: Group B Streptococcus Cultures. In Clinical Microbiology Procedures Handbook. Edited by AL Leber. Washington DC, ASM Press, 2016, section 3.9.2)

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Sunday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

3 to 5 days

Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

3 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Rochester

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

87081-Strep Grp B (S. agalactiae) culture

87077-Ident by MALDI-TOF mass spec (if appropriate)

87077-Bacteria identification (if appropriate)

87077-Identification Streptococcus (if appropriate)

87147 x 2-6-Serologic Agglut Method 4 Ident (if appropriate)

87153-Aerobe ident by sequencing (if appropriate)

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports