Useful For
Suggests clinical disorders or settings where the test may be helpful
Diagnosis of brucellosis in blood specimens
Reflex Tests
Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.
Test Id |
Reporting Name |
Available Separately |
Always Performed |
RMALD |
Ident by MALDI-TOF mass spec |
No, (Bill Only)
|
No |
ISAE |
Aerobe Ident by Sequencing |
No, (Bill Only)
|
No |
Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.
When this test is ordered, the reflex tests may be performed at an additional charge.
Method Name
A short description of the method used to perform the test
Conventional Culture Technique
NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.
Yes
Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test
Brucella Culture, B
Aliases
Lists additional common names for a test, as an aid in searching
Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.
When this test is ordered, the reflex tests may be performed at an additional charge.
Specimen Type
Describes the specimen type validated for testing
Whole Blood Culture
Ordering Guidance
Mayo Clinic Laboratories does not perform species identification of Brucella; these isolates should be submitted to the State Health Department laboratory.
Necessary Information
ORDER QUESTIONS AND ANSWERS
Question ID |
Description |
Answers |
Q00M0010 |
Specimen Source |
|
Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing
Container/Tube: Blood Isolator tube
Specimen Volume: Entire collection
Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Specimen Type |
Temperature |
Time |
Special Container |
Whole Blood Culture |
Ambient (preferred) |
24 hours |
|
Useful For
Suggests clinical disorders or settings where the test may be helpful
Diagnosis of brucellosis in blood specimens
Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.
When this test is ordered, the reflex tests may be performed at an additional charge.
Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Interpretation
Provides information to assist in interpretation of the test results
Isolation of a Brucella species indicates infection
Cultures of blood and/or bone marrow are positive in 70% to 90% of acute Brucella infections, but much less so in subacute or chronic infections. In these latter instances, culture yield is highest from the specific tissue involved, or serology may be necessary to establish diagnosis.
Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
Although Brucella species are relatively resistant to adverse environmental conditions, excessive delay in the transport of material for culture to the laboratory may result in a lower yield.
If a significant delay is expected, specimens should be refrigerated.
Clinical Reference
Recommendations for in-depth reading of a clinical nature
1. Mandell GL, Bennett JE, Dolin R: Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 4th ed. Churchill Livingstone; 1995:2053-2060
2. Procop GW, Church DL, Hall GS, et al, eds: Miscellaneous Fastidious Gram-Negative Bacilli. In: Koneman's Color Atlas and Textbook of Diagnostic Microbiology. 7th ed. Wolters Kluwer; 2017:472-595
Method Description
Describes how the test is performed and provides a method-specific reference
Specimens submitted in Isolator tubes are concentrated and inoculated onto blood and chocolate blood agar incubated at 35 degrees C with increased carbon dioxide (CO2). Cultures are incubated for 14 days before issuing a negative report.
Microorganisms recovered are identified by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry and/or nucleic acid sequencing of the 16S ribosomal RNA (rRNA) gene. Antimicrobial susceptibility testing is not performed on isolates of Brucella species.(Araj GF: Chapter 49: Brucella. In Manual of Clinical Microbiology. 12th edition. Edited by KC Carroll, MA Pfaller. Washington DC, American Society for Microbiology, 2019, pp 883-892)
PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information
No
Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.
14 to 17 days
Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
14 days
Rochester
Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.
- Authorized users can sign in to Test Prices for detailed fee information.
- Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
- Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.
Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.
Test Id |
Test Order Name |
Order LOINC Value
|
BRUCB |
Brucella Culture, B |
551-2 |
Result Id |
Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
BRUCB |
Brucella Culture, B |
551-2 |
Test Setup Resources
Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.
Excel |
Pdf
SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.
SI Normal Reports |
SI Abnormal Reports