Test Catalog

Test ID: PNPAN    
Peripheral Neuropathy Expanded Panel by Next-Generation Sequencing (NGS), Varies

Useful For Suggests clinical disorders or settings where the test may be helpful

Diagnosis of inherited peripheral neuropathies with isolated nerve involvement or associated with other organ system or associated with metabolic syndromes with known causal genes


A second-tier test for patients in whom previous targeted gene mutation analyses for specific inherited peripheral neuropathy-related genes were negative


Identifying mutations within genes known to be associated with inherited peripheral neuropathy, allowing for predictive testing of at-risk family members

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test includes next-generation sequencing and Sanger sequencing to evaluate for the genes listed on the panel. See Targeted Genes Interrogated by Peripheral Neuropathy Expanded Panel in Special Instructions for details regarding the targeted gene regions identified by this test.


Prior Authorization is available for this assay; see Special Instructions

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

See Hereditary Peripheral Neuropathy Testing Algorithm in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Custom Sequence Capture and Targeted Next-Generation Sequencing (NGS) followed by Polymerase Chain Reaction (PCR) and Sanger Sequencing when appropriate

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Peripheral Neuro Expanded Panel

Aliases Lists additional common names for a test, as an aid in searching

Hereditary sensory neuropathy
Hereditary spastic paraplegia
Distal hereditary motor neuropathy
Peripheral neuropathy
Inherited neuropathy
Familial neuropathy