Test Catalog

Test ID: BRST6    
Hereditary Breast Cancer 6 Gene Panel

Useful For Suggests clinical disorders or settings where the test may be helpful

Establishing a hereditary susceptibility to cancer


Identification of familial BRCA1, BRCA2, TP53, PTEN, CDH1, or STK11 mutation to allow for predictive testing in family members

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test includes next-generation sequencing, array comparative genomic hybridization, and multiplex ligation-dependent probe amplification to evaluate for mutations and large deletions/duplications in the BRCA1, BRCA2, TP53, PTEN (including the promoter), CDH1, and STK11 genes. Sanger sequencing may also be performed to confirm detected variants.


Prior Authorization is available for this assay; see Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Custom Sequence Capture and Targeted Next Generation Sequencing Followed by Polymerase Chain Reaction (PCR) and Sanger Sequencing and Gene Dosage Analysis by Array Comparative Genomic Hybridization (aCGH) or Multiplex Ligation-Dependent Probe Amplification (MLPA)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Hereditary Breast 6 Gene Panel

Aliases Lists additional common names for a test, as an aid in searching

Breast 6-Gene Panel
Breast Cancer
Breast and Ovarian Cancer Panel
Cowden syndrome
Hereditary Breast Cancer
Hereditary Breast and Ovarian Cancer
Hereditary Cancer Panel
Hereditary Diffuse Gastric Cancer
Li-Fraumeni syndrome
Next Generation Sequencing
Ovarian Cancer
Petuz-Jeghers syndrome
Targeted Gene Panel