Screening for hematuria, myoglobinuria, or intravascular hemolysis
Dipstick
Urine Hemoglobin
Urine
Container/Tube: Plastic urine container
Specimen Volume: 20 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
If not ordering electronically, complete, print, and send a Benign Hematology Test Request Form (T755) with the specimen.
4 mL
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Urine | Refrigerated (preferred) | 72 hours |
Screening for hematuria, myoglobinuria, or intravascular hemolysis
Free hemoglobin (Hb) in urine usually is the result of lysis of red blood cells present in the urine due to bleeding into the urinary tract (kidney, ureters, bladder). Less commonly, intravascular hemolysis (eg, transfusion reaction, hemolytic anemia, paroxysmal hemoglobinuria) may result in excretion of free Hb from blood into urine.
Injury to skeletal or cardiac muscle results in the release of myoglobin, which also is detected by this assay. Conditions associated with myoglobinuria include hereditary myoglobinuria, phosphorylase deficiency, sporadic myoglobinuria, exertional myoglobinuria in untrained individuals, crush syndrome, myocardial infarction, myoglobinuria of progressive muscle disease, and heat injury.
COLOR: Colorless, Yellow
CLARITY: Clear
CONCISTENCY: Not reported
HEMOGLOBIN: Negative
Red Blood Cells: <3 RBC/hpf
Free hemoglobin (Hb), in the presence of red blood cells (RBC), indicates bleeding into the urinary tract.
Free Hb, in the absence of RBC, is consistent with intravascular hemolysis.
Note: RBC may be missed if lysis occurred prior to analysis; the absence of RBC should be confirmed by examining a fresh specimen.
The test is equally sensitive to hemoglobin and to myoglobin. The presence of myoglobin may be confirmed by MYGLU / Myoglobin, Random, Urine.
Capoten (captopril) may reduce the test sensitivity.
Certain oxidizing contaminants, such as hypochlorite, may produce false-positive results.
Microbial peroxidase associated with urinary tract infection may cause a false-positive reaction.
1. Fairbanks, V.F. and Klee G.G., Textbook of Clinical Chemistry 1986, Chapter 15, p 1562
2. Brunzel N: Chemical examination of urine. In: Fundamentals of Urine and Body Fluids. 4th ed. 2018:85-125
The Clinitek Status+ analyzer is a reflectance spectrophotometer that analyzes the intensity and color of the light reflected from the reagent areas. No calculations are required.(Package insert: Multistix 10 SG Reagent Strip .AN30516J Siemens. Rev. 02/2011)
A microscopic examination is performed on urine sediments by conventional microscopy. All remaining urines have a manual microscopic examination performed on the sediment after centrifuging for 5 minutes at 1400 RPM.
Monday through Sunday
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.
81003
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
HGBQ | Hemoglobin, QL, U | 57751-0 |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
COLUR | Color, U | 5778-6 |
CLAUR | Clarity, U | 32167-9 |
CONUR | Consistency, U | In Process |
HGBH | Hemoglobin, QL, U | 57751-0 |
RBC6 | RBC, U | 13945-1 |