Test Catalog

Test Id : VRID2

Culture Referred for Identification, Virus

Useful For
Suggests clinical disorders or settings where the test may be helpful

Viral identification and confirmation

Reflex Tests
Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test Id Reporting Name Available Separately Always Performed
VID2 Additional Testing Virus Ident No, (Bill Only) No
SVIR Viral Smear, Shell Vial No, (Bill Only) No

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, the reflex tests may be performed and charged.

Special Instructions
Library of PDFs including pertinent information and forms related to the test

Method Name
A short description of the method used to perform the test

Shell Vial Assay for Appropriate Virus and/or Tube Cell Culture

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Culture Referred for ID, Virus

Aliases
Lists additional common names for a test, as an aid in searching

50017-VRID2

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, the reflex tests may be performed and charged.

Specimen Type
Describes the specimen type validated for testing

Varies

Ordering Guidance

Suspected isolates of the following viruses will not be accepted at Mayo Clinic Laboratories and should be submitted directly to your state health department or the CDC for confirmatory testing:

-Measles

-Mumps

-Ebola and other causative agents of viral hemorrhagic fevers

-Avian influenza

-Severe Acute Respiratory Syndrome (SARS)

-Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV)

Shipping Instructions

1. See Infectious Specimen Shipping Guidelines in Special Instructions.

2. Place specimen in a large infectious container (T146) and label as an etiologic agent/infectious substance.

Necessary Information

1. Specimen source is required and must include anatomical site of original specimen collected.

2. Isolate description is required. Include morphology and list any previous tests performed.

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Supplies: Infectious Container, Large (T146)

Specimen Type: Pure culture of organism from source cultured

Container/Tube: Cell (viral) culture tube

Specimen Volume: Entire specimen

Collection Instructions:

1. Organism must be in pure culture, actively growing.

2. Completely fill culture tube with appropriate culture medium before shipment.

Special Instructions
Library of PDFs including pertinent information and forms related to the test

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

Hemolysis NA
Lipemia NA
Icterus NA
Other Agar plate

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)
Refrigerated

Useful For
Suggests clinical disorders or settings where the test may be helpful

Viral identification and confirmation

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, the reflex tests may be performed and charged.

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Viruses are responsible for a broad spectrum of clinical symptoms and diseases. The most commonly isolated viruses are adenovirus, cytomegalovirus (CMV), enteroviruses, herpes simplex virus (HSV), influenza virus, parainfluenza virus (types 1-3), respiratory syncytial virus (RSV), and varicella-zoster virus (VZV).

 

Some viral infections can be treated with antiviral drugs. Early laboratory diagnosis by isolation may be helpful in the medical management of these patients.

 

Viruses that may be recovered in cell culture include adenovirus, CMV, enterovirus, HSV, VZV, RSV, influenza virus, and parainfluenza virus. HSV and enterovirus are the most commonly recovered viruses.

 

A number of viruses are not routinely detected in cell culture. These include Epstein-Barr virus (EBV), rubella virus (must order serology), human papillomavirus (HPV), Norwalk or norovirus, and West Nile virus.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Not applicable

Interpretation
Provides information to assist in interpretation of the test results

A positive result indicates that virus was present in the specimen submitted. Clinical correlation is necessary to determine the significance of the result.

 

Negative results may be seen in a number of situations including absence of viral disease, inability of the virus to grow in culture (examples of organisms not detected by culture include Epstein-Barr virus, rubella virus, human papilloma virus, norovirus and West Nile virus), and nonviable organisms submitted. Parainfluenza virus type 4 also may not be detected by viral culture.

Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Viral isolation and detection depends on the proper collection and transport of the specimen.

 

Some viruses (eg, cytomegalovirus) take up to 2 weeks to grow in viral cell culture. Molecular tests (ie, real-time PCR) should be used for rapid diagnosis.

Clinical Reference
Recommendations for in-depth reading of a clinical nature

1. Clinical and Laboratory Standards Institute (CLSI). Viral Culture. Proposed Guideline. 2005 CLSI document M41-P. CLSI, Wayne, PA

2. Ginocchio CC, Van Horn G, Harris PC: In Manual of Clinical Microbiology. Chapter 80: Reagents, stains, and cell culture: virology. 11th edition. Edited by J Versalovic, KC Carroll, et al. Washington, DC, ASM Press, 2015, pp 1422-1431

Special Instructions
Library of PDFs including pertinent information and forms related to the test

Method Description
Describes how the test is performed and provides a method-specific reference

Results of viral cultures are reported from presence of typical cytopathic effect, and/or confirmation by immunofluorescence with specific antisera, or rapid PCR, depending on the specific virus.(Smith TF: Antibody-enhanced detection of viruses in cell cultures. In Manual of Clinical Laboratory Immunology. Fifth edition. Edited by NR Rose, EC de Macario, JD Folds, et al: Washington, DC, ASM Press, 1997, pp 618-624)

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Sunday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

14 to (Positives are reported when detected) 15 days

Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

Until reported

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Rochester

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

87253-Additional Testing Virus Identification (if appropriate)

87254-Viral Smear, Shell Vial(if appropriate)

LOINC® Information

Test Id Test Order Name Order LOINC Value
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.
VRID2 Culture Referred for ID, Virus 6584-7
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
VRID2 Culture Referred for ID, Virus 6584-7

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Create a PDF

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports