Test Catalog

Test ID: MLH1Z    
MLH1 Gene, Full Gene Analysis

Useful For Suggests clinical disorders or settings where the test may be helpful

Determining whether absence of MLH1 protein, by immunohistochemistry in tumor tissue, is associated with a germline mutation in the affected individual

 

Establishing a diagnosis of Lynch syndrome/hereditary nonpolyposis colorectal cancer

 

Identification of familial MLH1 mutation to allow for predictive testing in family members

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

Prior Authorization is available for this assay; see Special Instructions.

Additional Tests Lists tests that are always performed, at an additional charge, with the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
COLABHereditary Colon Cancer CGH ArrayYes, (Order FMTT)Yes

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, comparative genomic hybridization array will always be performed at an additional charge.

 

See Lynch Syndrome Testing Algorithm in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Polymerase Chain Reaction (PCR) Amplification/DNA Sequencing

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

MLH1 Gene, Full Gene Analysis

Aliases Lists additional common names for a test, as an aid in searching

Colon Cancer Gene Testing
Hereditary Non-Polyposis Colorectal Cancer (HNPCC)
Hereditary Nonpolyposis Colorectal Cancer (HNPCC)
hMLH1 Genotyping
HNPCC (Hereditary Nonpolyposis Colorectal Cancer) Gene Testing
Lynch Syndrome
MLH1 Gene Testing
MLHMS