TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: NGHHA    
Hereditary Hemolytic Anemia Comprehensive Panel, Next-Generation Sequencing, Varies

Method Description Describes how the test is performed and provides a method-specific reference

This next-generation sequencing assay is performed to test for the presence of a mutation in targeted regions of the following 39 genes: AK1, ALDOA, ANK1, C15ORF41, CD59, CDAN1, EPB41, EPB42, FANCA, FANCC, FANCG, G6PD, GATA1, GCLC, GPI, GSR, GSS, GYPC, HBB, HBD, HK1, HMOX1, KIF23, KLF1, NT5C3A, PFKM, PGK1, PIEZO1, PKLR, RHAG, RPS19, SEC23B, SLC2A1, SLC4A1, SPTA1, SPTB, STOM, TPI1, and UGT1A1. See Targeted Genes Interrogated by NGHHA Next-Generation Sequencing in Genetics Information in Special Instructions for details regarding the targeted gene regions identified by this test. This is a laboratory-developed test using Research Use Only reagents.

 

Next-generation sequencing (NGS) is performed using the Illumina MiSeq instrument with paired-end, 151-base pair (bp) reads. The DNA is prepared for NGS using a custom Agilent SureSelect Target Enrichment System. Data is analyzed with the CLC Genomics Server Program. Supplemental or confirmatory Sanger sequencing is performed when necessary.(Unpublished Mayo method)

PDF Report Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday

Report Available The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

8 to 10 weeks

Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

DNA 3 months

Performing Laboratory Location Indicates the location of the laboratory that performs the test

Rochester