Web: | mayocliniclabs.com |
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Email: | mcl@mayo.edu |
Telephone: | 800-533-1710 |
International: | +1 855-379-3115 |
Values are valid only on day of printing. |
A PCR-based assay employing Scorpions real-time PCR and allele-specific PCR technologies is used to test for 29 mutations within exons 18 through 21 of the EGFR gene:
G719A | 2239_2256del8 |
G719S | 2239_2248TTAAGAGAAG->C |
G719C | 2239_2258->CA |
2235_2249del15 | 2240_2251del12 |
2235_2252->AAT | 2240_2257del8 |
2236_2253del18 | 2240_2254del15 |
2237_2251del15 | 2239_2251->C |
2237_2254del18 | 2307_2308ins9 |
2237_2255->T | 2310_2311insGGT |
2236_2250del15, | 2319_2320insCAC |
2238_2255del18, | S768I |
2238_2248->GC | T790M |
2238_2252->GCA | L858R |
2239_2247del9 | L861Q |
2239_2253del15 |
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A pathology review and macro dissection to enrich for tumor cells is performed prior to DNA extraction.(Package insert: EGFR RGQ PCR Kit, Qiagen, Valencia, CA, 2011)
Monday through Friday; 10 a.m.