Test Catalog

Test ID: MMOGA    
Monoclonal Gammopathy Monitoring, Serum

Useful For Suggests clinical disorders or settings where the test may be helpful

Monitoring patients with monoclonal gammopathies


This test is not recommended to screen or establish a first-time diagnosis for a monoclonal gammopathy

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
TPETotal ProteinYes, (Order TP)Yes
SPEProtein ElectrophoresisNoYes

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
MPTSM-protein Isotype MALDI-TOF MS, SNoNo
IMFXImmunofixationYes, (Order IMFXO)No

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This test includes total protein and serum protein electrophoresis.


If a discrete electrophoresis band is not identified, the laboratory will evaluate the serum protein electrophoresis and, if necessary, perform M-protein isotype at an additional charge.


If a light chain is identified without a corresponding heavy chain during initial testing, immunofixation with IgD and IgE antisera will be performed at an additional charge.


If a history of an IgD or IgE has been previously established and no M-spike is seen on electrophoresis, immunofixation with IgD and IgE antisera will be performed at an additional charge.

Method Name A short description of the method used to perform the test

TPE: Biuret

SPE: Agarose Gel Electrophoresis

MPTS: Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Monoclonal Gammopathy Monitor, S

Aliases Lists additional common names for a test, as an aid in searching

Mass Fix
Serum protein electrophoresis
Protein electrophoresis
Light chain deposition disease
MGUS follow-up
Myeloma treatment response