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Test ID: WARSV    
Warfarin Response Genotype, Varies

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Useful For Suggests clinical disorders or settings where the test may be helpful

Identifying patients who may require warfarin dosing adjustments(3,4) including:

-Patients being started on a first prescription for warfarin

-Patients who have previously been prescribed warfarin and have required multiple dosing adjustments to maintain the international normalized ratio in the target range

-Patients with a history of thrombosis or bleeding when taking warfarin

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test is used for assessing CYP2C9, VKORC1, CYP4F2, and rs12777823 for variants affecting the metabolism of warfarin (Coumadin). This assay should be ordered on patients who are receiving warfarin for the first time or who are experiencing difficulties in maintaining the international normalized ratio (INR) in the therapeutic range.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Real-Time Polymerase Chain Reaction (PCR) with Allelic Discrimination Analysis

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Warfarin Response Genotype

Aliases Lists additional common names for a test, as an aid in searching

2C9
Coumadin Genotype
Vitamin K Epoxide Reductase Subunit 1
Vitamin K Genotype (VKORC1)
Warfarin Genotype
CYP4F2
Cytochrome P450 2C9 (CYP2C9) Genotyping
rs 12777823
VKORC1
Warfarin Sensitivity
Warfarin Resistance