Test Catalog

Test ID: SLC1V    
Solute Carrier Organic Anion Transporter Family Member 1B1 (SLCO1B1) Genotype, Statin, Varies

Useful For Suggests clinical disorders or settings where the test may be helpful

Predicting risk for statin-associated myopathy in patients beginning statin therapy, especially simvastatin therapy

 

Determining a potential statin lipid lowering response, especially when using pravastatin

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This is a pharmacogenomics test for genotype for the rs4149056 (c.521T->C) variant found in the *5, *15, and *17 alleles, and rs4149015 (c.-910G->A) found in the *17 and *21 alleles. Presence of the *5 allele is associated with an increased risk for simvastatin-associated myopathy.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Real-Time Polymerase Chain Reaction (PCR) with Allelic Discrimination Analysis

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

SLCO1B1 Genotype

Aliases Lists additional common names for a test, as an aid in searching

OATP1B1
SLCO1B1
Simvastatin
Statin