Test Catalog

Test ID: CVID    
Common Variable Immunodeficiency Confirmation Flow Panel

Useful For Suggests clinical disorders or settings where the test may be helpful

Screening for common variable immunodeficiency (CVID)


Identifying defects in TACI and BAFF-R in patients presenting with clinical symptoms and other laboratory features consistent with CVID


Evaluating B cell immune competence by assessing expression of BAFF-R and TACI proteins


Useful for assessing BAFF-R and TACI protein expression and frequency of B cells bearing these receptors. TNFRSF13C (BAFF-R) and TNFRSF13B (TACI) gene mutations have been described in a small subset of patients with humoral immunodeficiencies classified as CVID. The majority of TNFRSF13B mutations preserve TACI protein expression and require genetic testing to identify pathogenic or potentially pathogenic mutations/variants.

Method Name A short description of the method used to perform the test

Fluorescent Flow Cytometry

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

CVID Confirmation Flow Panel