Test Catalog

Test ID: BDIAL    
Bleeding Diathesis Profile, Limited

Useful For Suggests clinical disorders or settings where the test may be helpful

Detection of the more common potential causes of abnormal bleeding (eg, factor deficiencies/hemophilia, von Willebrand disease, factor-specific inhibitors) and a simple screen to evaluate for an inhibitor or severe deficiency of factor XIII (rare).

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
PTCProthrombin Time (PT), PYes, (order PTTP)Yes
APTTBActivated Partial Thrombopl Time, PYes, (order APTTP)Yes
TTThrombin Time (Bovine), PYesYes
DIRMD-Dimer, PYes, (order DDITT)Yes
SFMSoluble Fibrin MonomerNoYes
FIBCFibrinogen, PYes, (order FIBTP)Yes
F8ACoag Factor VIII Activity Assay, PYesYes
VWAGvon Willebrand Factor Ag, PYesYes
VWFXvon Willebrand Factor Activity, PYesYes
FXIIIFactor XIII(13),ScrnNoYes
CCCSpecial Coagulation InterpretationNoYes

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
IBETHBethesda UnitsNoNo
F8ISCoag Factor VIII Assay Inhib Scrn,PNoNo
RISTRistocetin Cofactor, PNoNo
FACTVCoag Factor V Assay, PYesNo
F_7Coag Factor VII Assay, PYesNo
F_9Coag Factor IX Assay, PYesNo
F_10Coag Factor X Assay, PYesNo
F_11Coag Factor XI Assay, PYesNo
F_12Coag Factor XII Assay, PYesNo
RPTLReptilase Time, PYesNo
APSMAlpha-2 Plasmin Inhibitor, PYesNo
F_2Coag Factor II Assay, PYesNo
F9_ISFactor IX Inhib ScrnNoNo
11_ISFactor XI Inhib ScrnNoNo
F2_ISFactor II Inhib ScrnNoNo
F5_ISFactor V Inhib ScrnNoNo
F7_ISFactor VII Inhib ScrnNoNo
10_ISFactor X Inhib ScrnNoNo
PNPPlatelet Neutralization ProcedureNoNo
PTMXPT Mix 1:1NoNo
DRVTCDRVVT ConfirmationNoNo
STLAStaclot LA, PNoNo
DRVTDilute Russells Viper Venom Time, PYes, (Order DRVTI)No
VWFMvon Willebrand Factor Multimer, PYes, (order VWFM2)No

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Initial testing includes: prothrombin time (PT), activated partial thromboplastin time, thrombin time (bovine), fibrinogen, D-dimer, soluble fibrin monomer, coagulation factor VIII activity assay, von Willebrand factor antigen, von Willebrand factor activity, factor XIII screen, and special coagulation interpretation.  

If PT is > or =14 seconds, PT mix will be performed.

If APTT is >36 seconds, APTT mix and DRVVT will be performed.

If DRVVT ratio is > or =1.2, DRVVT mix will be performed.

If APTT mix is >36 seconds with no evidence of heparin in samples, platelet neutralization procedure will be performed.

If DRVVT ratio is > or =1.2, DRVVT mix and DRVVT confirmation will be performed.

If von Willebrand factor activity assay is <55%, von Willebrand factor ristocetin cofactor activity assay will be performed.  

If von Willebrand factor (VWF) antigen is <55%, the VWF activity is <55%, or the VWF activity:VWF antigen ratio is <0.8, VWF multimer analysis will be performed.

If appropriate, coagulation factor assays or Staclot LA will be performed at an additional charge to clarify significant abnormalities in the screening clotting times.

If factor VIII result is <55%, the factor VIII inhibitor screen may be performed along with the Bethesda titering assay, if inhibitor screen is positive.


See Hemophilia Testing Algorithm in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test


RIST: Ristocetin Induced Agglutination of Washed Normal Platelets

VWAG, VWFX, DIRM, SFM: Latex Immunoassay (LIA)

FIBC: Clauss

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Bleeding Diath Prof, Limited

Aliases Lists additional common names for a test, as an aid in searching

Bleeding Diathesis Profile, Limited