Web: | mayocliniclabs.com |
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Email: | mcl@mayo.edu |
Telephone: | 800-533-1710 |
International: | +1 855-379-3115 |
Values are valid only on day of printing. |
Screening for the presence of IgM-class antibodies to Zika virus
This assay is a screening test for IgM-class antibodies to Zika virus. A presumptive positive result by this assay is not diagnostic for Zika virus infection and confirmatory testing may be required as determined by your local health department. Confirmatory testing by a molecular assay for detection of Zika virus RNA may also be considered.
This assay should be used in patients presenting at least 2 weeks post-symptom onset or last possible exposure to Zika virus. Reverse transcription-polymerase chain reaction (RT-PCR) for Zika virus RNA detection should be ordered in patients with less than 2 weeks of symptoms or postexposure.
A single negative result by the Zika IgM enzyme-linked immunosorbent assay (ELISA) should not be used to rule-out infection as the specimen may have been collected prior to the development of detectable antibodies.
The following algorithms are available in Special Instructions:
IgM Antibody Capture Enzyme-Linked Immunosorbent Assay (MAC-ELISA)