Referred Tests
| Web: | mayocliniclabs.com |
|---|---|
| Email: | mcl@mayo.edu |
| Telephone: | 800-533-1710 |
| International: | +1 855-379-3115 |
| Values are valid only on day of printing. | |
Test ID: MZIKV
Zika Virus IgM Antibody Capture MAC-ELISA, Serum
Useful For 
Suggests clinical disorders or settings where the test may be helpful
Screening for the presence of IgM-class antibodies to Zika virus in patients presenting with symptoms for 14 or more days
Establishment of baseline serologic levels of IgM-class antibodies to Zika virus in women who have traveled to a Zika virus endemic region or who have had sexual exposure to Zika virus and who are considering conception
Highlights
This assay is a screening test for IgM-class antibodies to Zika virus. A presumptive positive result by this assay is not diagnostic for Zika virus infection and requires confirmatory testing by plaque reduction neutralization testing (PRNT) performed at the CDC or a CDC-designated laboratory. Confirmatory testing by a molecular assay for detection of Zika virus RNA may also be considered.
This assay should be used in patients presenting at least 2 weeks postsymptom onset or last possible exposure to Zika virus. Reverse transcription-polymerase chain reaction (RT-PCR) for Zika virus RNA detection should be ordered in patients with less than 2 weeks of symptoms or postexposure.
A single negative result by the Zika IgM ELISA should not be used to rule-out infection as the specimen may have been collected prior to the development of detectable antibodies.
Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.
The following algorithms are available in Special Instructions:
-Assessment for Zika Virus Infection in Nonpregnant Individuals
Special Instructions Library of PDFs including pertinent information and forms related to the test
Method Name A short description of the method used to perform the test
IgM Antibody Capture Enzyme-Linked Immunosorbent Assay (MAC-ELISA)