Referred Tests
| Web: | mayocliniclabs.com |
|---|---|
| Email: | mcl@mayo.edu |
| Telephone: | 800-533-1710 |
| International: | +1 855-379-3115 |
| Values are valid only on day of printing. | |
Test ID: F7NGS
Factor VII Deficiency, F7 Gene, Next-Generation Sequencing, Varies
Useful For 
Suggests clinical disorders or settings where the test may be helpful
Genetic confirmation of a factor VII deficiency diagnosis with the identification of a known or suspected pathogenic alteration in the F7 gene
Carrier testing for close family members of an individual with a factor VII deficiency diagnosis
This test is not useful for prenatal diagnosis.
Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request
This test detects pathogenic alterations in the F7 gene to delineate the underlying molecular defect in a patient with a laboratory diagnosis of Factor VII deficiency (F7D), a rare bleeding disorder.
The gene target for this test is:
Gene name (transcript): F7 (GRCh37 [hg19] NM_000131)
Chromosomal location: 13q34
Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.
The clinical workup for factor VII deficiency (F7D) begins with coagulation testing consisting of coagulation factor VII assay (see F_7 / Coagulation Factor VII Activity Assay, Plasma).
Genetic testing for F7D is indicated if:
-Factor VII activity is reduced (less than 65% of normal)
-Acquired causes of FVII deficiency have been excluded
Special Instructions Library of PDFs including pertinent information and forms related to the test
Method Name A short description of the method used to perform the test
Custom Sequence Capture and Targeted Next-Generation Sequencing (NGS) Followed by Polymerase Chain Reaction (PCR) and Sanger Sequencing when appropriate
NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.
Reporting Name Lists a shorter or abbreviated version of the Published Name for a test
Aliases Lists additional common names for a test, as an aid in searching
F7D