Referred Tests
| Web: | mayocliniclabs.com |
|---|---|
| Email: | mcl@mayo.edu |
| Telephone: | 800-533-1710 |
| International: | +1 855-379-3115 |
| Values are valid only on day of printing. | |
Test ID: F10NG
Factor X Deficiency, F10 Gene, Next-Generation Sequencing, Varies
Useful For 
Suggests clinical disorders or settings where the test may be helpful
Genetic confirmation of a factor X deficiency diagnosis with the identification of a known or suspected pathogenic alterations in the F10 gene
Carrier testing for close family members of an individual with a factor X deficiency diagnosis
This test is not intended for prenatal diagnosis.
Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request
This test detects pathogenic alterations within the F10 gene to delineate the underlying molecular defect in a patient with a laboratory diagnosis of factor X deficiency (FXD), a rare bleeding disorder.
The gene target for this test is:
Gene name (transcript): F10 (GRCh 37 [hg19] NM_000504)
Chromosomal location: 13q34
Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.
The clinical workup for factor X deficiency (F10D) begins with special coagulation testing for factor X. See F_10 / Coagulation Factor X Activity Assay, Plasma.
Genetic testing for F10D is indicated if:
-Factor X clotting activity is reduced (less than 80% of normal)
-Acquired causes of factor X deficiency have been excluded (eg, liver disease, warfarin therapy, vitamin K deficiency, systemic amyloidosis, and inhibitors)
Special Instructions Library of PDFs including pertinent information and forms related to the test
Method Name A short description of the method used to perform the test
Custom Sequence Capture and Targeted Next-Generation Sequencing (NGS) followed by Polymerase Chain Reaction (PCR) and Sanger Sequencing when appropriate
NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.
Reporting Name Lists a shorter or abbreviated version of the Published Name for a test
Aliases Lists additional common names for a test, as an aid in searching
Factor X Deficiency
Stuart-Prower Factor deficiency
F10D
F10