Test Catalog

Test ID: TPNUV    
Thiopurine Methyltransferase (TPMT) and Nudix Hydrolase (NUDT15) Genotyping, Varies

Useful For Suggests clinical disorders or settings where the test may be helpful

Predicting potential for toxicity to thiopurine drugs (6-mercaptopurine, 6-thioguanine, and azathioprine)

Highlights

This test includes genotyping of TPMT and NUDT15, both of which affect metabolism of thiopurine drugs.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Real-Time Polymerase Chain Reaction (PCR) With Allelic Discrimination Analysis

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

TPMT and NUDT15 Genotype

Aliases Lists additional common names for a test, as an aid in searching

6-Mercaptopurine
6-Thioguanine
Acute Lymphoblastic Leukemia (ALL)
Azathioprine
Crohn's Disease
Rheumatoid Arthritis
Inflammatory Bowel Disease (IBD)
NUDT15
TPMT
Thiopurine
Ulcerative Colitis