TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: PRCNG    
PROCR Gene, Next-Generation Sequencing, Varies

Useful For Suggests clinical disorders or settings where the test may be helpful

Ascertaining a pathogenic alteration in the PROCR gene in patients with recurrent unprovoked venous thromboembolism (VTE)before the age of 40, a strong family history of unexplained and unprovoked VTE, and prior genetic testing for more common genetic variants associated with thrombophilia that does not correlate with the severity of the patient’s thrombophilia or clinical presentation

 

This test is not intended for prenatal diagnosis

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test detects alterations in the PROCR gene associated with increased risk for venous thromboembolism.

 

The gene target for this test is:

Gene name (transcript): PROCR (GRCh37 [hg19] NM_006404)

Chromosomal location: 20q11.22

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

No screening tests exist for defects in PROCR. A set of clinical guidelines from the British Society for Haematology on testing for heritable thrombophilia is freely available.(1) A genetic consultation is strongly recommended prior to ordering PROCR sequencing.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Custom Sequence Capture and Targeted Next-Generation Sequencing (NGS) Followed by Polymerase Chain Reaction (PCR) and Sanger Sequencing When Appropriate

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

PROCR Gene, Full Gene NGS

Aliases Lists additional common names for a test, as an aid in searching

Protein C Receptor
Endothelial Protein C Receptor
EPCR
Heritable thrombophilia