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As an adjunct to cytologic examination of fine-needle aspiration specimens in athyrotic individuals treated for medullary thyroid carcinoma to confirm or exclude metastases in enlarged or ultrasonographically suspicious lymph nodes
Measurement of calcitonin in fine-needle aspiration biopsy (FNAB)-needle washes improves the evaluation of suspicious lymph nodes in patients with a history of medullary thyroid carcinoma (MTC) when used in combination with cytology.
Calcitonin in needle washes is particularly useful in cases where the cytology result is nondiagnostic or indeterminate.
In athyrotic patients with a history of MTC, a fine-needle aspiration calcitonin value of 5.0 pg/mL and higher is suggestive of the presence of metastatic MTC in the biopsied lymph node.
Electrochemiluminescence Immunoassay