TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
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Test ID: COVNG    
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage, Clade, and Spike Gene Mutation Detection, Next-Generation Sequencing, Varies

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Useful For Suggests clinical disorders or settings where the test may be helpful

Distinguish between persistent infection with the same viral strain and re-infection with a new viral strain in an individual with recurrent positive molecular test results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

 

Detection and identification of vaccine-escape SARS-CoV-2 variants with spike (S) gene mutations of interest

 

Detection and identification of SARS-CoV-2 variants containing S gene mutations of interest that reduce the efficacy of vaccine-induced antibodies, convalescent plasma, and/or monoclonal antibody therapy for COVID-19

Highlights

This test uses polymerase chain reaction (PCR) to amplify multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genetic sequences covering 99.9% of the viral genome, followed by a next-generation sequencing assay with sequence analyses to determine the Pangolin lineage, NextClade clade assignment, and alterations of the viral spike (S) protein-encoding codons in known SARS-CoV-2 RNA-positive respiratory tract specimens. Testing is more likely to be successful in positive specimens with viral target cycle threshold (Ct) values of less than or equal to 30.0.

Method Name A short description of the method used to perform the test

Reverse Transcription Polymerase Chain Reaction (RT-PCR) followed by Next-Generation Sequencing

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

No

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

SARS-CoV-2 Lineage, Clade, S Mut, V

Aliases Lists additional common names for a test, as an aid in searching

Coronavirus
COVID
COVID Variant
COVID-19
S gene mutation
SARS
SARS-CoV-2
SARS-CoV-2 clade
SARS-CoV-2 lineage
SARS-CoV-2 variant
Next Gen Sequencing