Test Catalog

Test ID: PEISO    
Protein Electrophoresis and Isotype, Serum

Useful For Suggests clinical disorders or settings where the test may be helpful

Diagnosis of monoclonal gammopathies, when used in conjunction with locally performed serum free light chain studies (performed at client site)

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
TMABTherapeutic Antibody Administered?NoYes
TPETotal ProteinYes, (Order TP)Yes
SPEProtein ElectrophoresisNoYes
MPTSM-protein Isotype MALDI-TOF MS, SYes, (Order MALD)Yes

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
IFXEDImmunofixation Delta and Epsilon, SYesNo

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This test includes total protein, serum protein electrophoresis, and heavy and light chain typing (kappa and lambda).


If a light chain is identified without a corresponding heavy chain during initial testing, immunofixation with IgD and IgE antisera will be performed at an additional charge.


The following algorithms are available in Special Instructions:

-Laboratory Approach to the Diagnosis of Amyloidosis

-Laboratory Screening Tests for Suspected Multiple Myeloma

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

TPE: Colorimetric, Biuret

SPE: Agarose Gel Electrophoresis

MPTS: Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Prot Electrophoresis and Isotype, S

Aliases Lists additional common names for a test, as an aid in searching

IFE (Immunofixation Electrophoresis)
Immunoelectrophoresis, Serum
Immunofixation Electrophoresis (IFE)
Immunofixation, Serum
MGUS (Monoclonal Gammopathy of Unknown Significance)
Monoclonal Protein Study
Multiple Myeloma
Special Protein Studies