Web: | mayocliniclabs.com |
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Email: | mcl@mayo.edu |
Telephone: | 800-533-1710 |
International: | +1 855-379-3115 |
Values are valid only on day of printing. |
Investigating patients with suspected or proven thymoma, whether or not symptoms or signs of myasthenia gravis (MG) are present
Serially monitoring patients for recurrence or metastasis after removal of thymoma
Providing a quantitative autoantibody baseline for future comparisons in monitoring a patient's clinical course and the response to thymectomy and immunomodulatory treatment
Assessing the likelihood of occult thymoma in a patient with an acquired disorder of neuromuscular or autonomic transmission
Evaluating bone marrow transplant recipients with suspected graft-versus-host disease, particularly if there is evidence of weakness
Confirming that a recently acquired neurological disorder has an autoimmune basis (eg, MG or dysautonomia)
Test ID | Reporting Name | Available Separately | Always Performed |
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MGETI | MG Thymoma Interpretation, S | No | Yes |
ARBI | ACh Receptor (Muscle) Binding Ab | Yes | Yes |
ARMO | ACh Receptor (Muscle) Modulating Ab | No | Yes |
STR | Striational (Striated Muscle) Ab, S | Yes | Yes |
CRMWS | CRMP-5-IgG Western Blot, S | Yes | Yes |
GANG | AChR Ganglionic Neuronal Ab, S | No | Yes |
VGKC | Neuronal (V-G) K+ Channel Ab, S | No | Yes |
GD65S | GAD65 Ab Assay, S | Yes | Yes |
Recommended for investigation of: 1) a patient with suspected or proven thymoma, whether or not symptoms or signs of myasthenia gravis (MG) are present (also of value for serially monitoring patients after removal of thymoma; a rising autoantibody titer may herald tumor persistence or recurrence), or emergence of an unrelated neoplasm and 2) a bone marrow transplant recipient with suspected graft-versus-host disease, particularly if there is evidence of weakness.
See Myasthenia Gravis: Thymoma Diagnostic Algorithm in Special Instructions.
ARBI, ARMO, GANG, GD65S, VGKC: Radioimmunoassay (RIA)
STR: Enzyme Immunoassay (EIA)
CRMWS: Western Blot