Web: | mayocliniclabs.com |
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Email: | mcl@mayo.edu |
Telephone: | 800-533-1710 |
International: | +1 855-379-3115 |
Values are valid only on day of printing. |
Confirmation of suspected clinical diagnosis of Li-Fraumeni syndrome or Li-Fraumeni-like syndrome
Identification of familial TP53 variant to allow for predictive testing in family members
Predictive testing of an asymptomatic child is not recommended.
This test evaluates for the presence of germline TP53 variants associated with Li Fraumeni syndrome.
For patients with a history of hematologic malignancy and/or bone marrow transplant, consultation with the laboratory is required prior to submitting a specimen.
Test ID | Reporting Name | Available Separately | Always Performed |
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COLAB | Hereditary Colon Cancer CGH Array | Yes, (order FMTT) | Yes |
When this test is ordered, comparative genomic hybridization array will always be performed at an additional charge.
See TP53 Mutation Testing Analysis in Special Instructions.
Polymerase Chain Reaction (PCR) Amplification followed by DNA Sequencing
COLAB: Gene Dosage Analysis by Array Comparative Genomic Hybridization (aCGH)