Test Catalog

Test ID: IMRGF    
Imatinib Mesylate Responsive Genes, FISH, Varies

Useful For Suggests clinical disorders or settings where the test may be helpful

Detecting a neoplastic clone associated with the common chromosome abnormalities seen in patients with acute leukemia or other myeloid malignancies

                             

Tracking known chromosome abnormalities and response to therapy in patients with myeloid malignancies

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
_PBCTProbe, +2No, (Bill Only)No
_PADDProbe, +1No, (Bill Only)No
_PB02Probe, +2No, (Bill Only)No
_PB03Probe, +3No, (Bill Only)No
_IL25Interphases, <25No, (Bill Only)No
_I099Interphases, 25-99No, (Bill Only)No
_I300Interphases, >=100 No, (Bill Only)No

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This test includes a charge for application of the first probe set (2 FISH probes) and professional interpretation of results.

 

Additional charges will be incurred for all reflex probes performed. Analysis charges will be incurred based on the number of cells analyzed per probe set. If no cells are available for analysis, no analysis charges will be incurred.

 

This assay includes testing for the following abnormalities using the probes listed:

ABL2 (1q25) rearrangement

FIP1L1/CHIC2/PDGFRA (4q12) rearrangement (CHIC2 deletion)

PDGFRB (5q33) rearrangement

ABL1 (9q34) rearrangement

 

If an ABL1 rearrangement is identified, reflex testing will be performed using the BCR/ABL1 dual-color, double fusion FISH probe set to evaluate for the presence or absence of BCR/ABL1 fusion.

 

If the patient is being tracked for known abnormalities, indicate which probes should be used.

Method Name A short description of the method used to perform the test

Fluorescence In Situ Hybridization (FISH)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Imatinib Mesylate Resp Genes, FISH

Aliases Lists additional common names for a test, as an aid in searching

ABL1 (9q34) rearrangement
ABL2 (1q25) rearrangement or ARG rearrangement
CHIC2 (4q12) deletion
FIP1L1/CHIC2/PDGFRA
Hypereosinophilic Syndrome (HES)
PDGFRB (5q33) rearrangement