TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: FIBR    
Fibroblast Culture, Tissue

Useful For Suggests clinical disorders or settings where the test may be helpful

Obtaining cultured cells for specialized testing including enzymatic and molecular genetic

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This processing test is for culturing skin fibroblasts or other biopsy for biochemical or molecular genetic studies. No analysis or interpretation of results is performed.

                                                                

When this test is ordered, cryopreservation will always be performed at an additional charge. However, for multiple assays on a patient utilizing the ordered fibroblast culture, only 1 culture is required regardless of the number of assays ordered.

 

Once confluent flasks are established, the cultures are sent to other laboratories, either within Mayo Clinic or to external sites, based on the specific testing requested.

If viable cells are not obtained within 30 days, client will be notified.

 

Mycoplasma screening will be performed on all successfully grown fibroblast cultures. If Mycoplasma is detected, all pending fibroblast clinical testing will be cancelled and the samples will be discarded.

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Cultures of skin fibroblasts are useful for specialized tests requiring skin cells. These cells can be cultured and tested at Mayo Clinic or sent to external laboratories  performing these specialized tests. In addition, cells are frozen for at least 3 years for potential future studies on cultured cells or for molecular genetic testing.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Not applicable

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Potential interfering factors:

-Lack of viable cells

-Bacterial contamination

-Failure to transport tissue in an appropriate media

-Excessive transport time

-Exposure of the specimen to temperature extremes (freezing or >30 degrees C)

-Improper packaging may result in broken or leaky specimen containers or contamination of specimens during transport

Special Instructions Library of PDFs including pertinent information and forms related to the test