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Test Catalog

Test ID: FPD2U    
Prostaglandin D2 (PG D2), Urine

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Prostaglandins are fatty acids derived from arachidonic acid metabolism.  They are closely related to the Thromboxanes and Leukotrienes.  Prostaglandin D2 is derived mainly from Prostaglandin H2, and is metabolized to Dihydroketo Prostaglandin D2.  Prostaglandin D2 is excreted directly into the urine.  The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach.  Prostaglandin D2 is the major Prostaglandin produced by uterine tissue.  Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent.  It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and indomethacin.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

No reference intervals available for this test.