Referred Tests
| Web: | mayocliniclabs.com |
|---|---|
| Email: | mcl@mayo.edu |
| Telephone: | 800-533-1710 |
| International: | +1 855-379-3115 |
| Values are valid only on day of printing. | |
Test ID: FPPCA
PCA3 (Prostate Cancer Antigen 3)
Clinical Information 
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Prostate cancer antigen 3 (PCA3, also known as Differential Display Code 3 or DD3) is a prostate-specific gene that was present in 95% of prostate cancer samples initially studied, and significantly over-expressed in cancer versus benign tissue. PCA3 is known to be a non-coding messenger ribonucleic acid (mRNA) with no resultant protein. Clinically, PCA3 mRNA is detectable in the urine and appears to be independent of prostate volume and serum PSA. The PCA3 urinary assay is reported out as a ratio of PCA3 mRNA to PSA mRNA.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
A score less than 25 is considered negative
A score greater than or equal to 25 is considered positive