TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: ICRU    
Iodine/Creatinine Ratio, Random, Urine

Useful For Suggests clinical disorders or settings where the test may be helpful

Assessment of iodine toxicity or recent exposure when a 24-hour urine cannot be collected

 

Monitoring iodine excretion rate as index of replacement therapy when a 24-hour urine cannot be collected

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Iodine is an essential element for thyroid hormone production.

 

The measurement of urinary iodine serves as an index of adequate dietary iodine intake.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

0-17 years: not established

> or = 18 years: <584 mcg/g creatinine

Interpretation Provides information to assist in interpretation of the test results

Measurement of urinary iodine excretion provides the best index of dietary iodine intake and deficiency is generally indicated when the concentrations are below 100 mcg/L. For deficiency, 10 repeat random urines are recommended.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Administration of iodine-based contrast media and drugs containing iodine, such as amiodarone, will yield elevated results.

Clinical Reference Recommendations for in-depth reading of a clinical nature

1. Nader R, Horwath AR, Wittwer CT: Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Sixth edition. St. Louis. Elsevier 2017

2. Knudsen N, Christiansen E, Brandt-Christensen M, et al: Age- and sex-adjusted iodine/creatinine ratio. A new standard in epidemiological surveys? Evaluation of three different estimates of iodine excretion based on casual urine samples and comparison to 24 h values. Eur J Clin Nutr 2000;54:361-363

3. Liberman CS, Pino SC, Fang SL, et al: Circulating iodine concentrations during and after pregnancy. J Clin Endocrinol Metab 1998;83:3545-3549

4. Pfeiffer CM, Sternberg MR, Schleicher RL, et al: CDC’s Second National Report on Biochemical Indicators of Diet and Nutrition in the US Population is a valuable tool for researchers and policy makers. J Nutr 2013;143(6):938S-947S

Special Instructions Library of PDFs including pertinent information and forms related to the test