Test Catalog

Test ID: CULTU    
Culture for Genetic Testing, Tumor Tissue

Useful For Suggests clinical disorders or settings where the test may be helpful

Producing tumor cell cultures that can be used for genetic analysis

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test is for the culturing of tumor cells for cytogenetic, molecular genetics, or other testing. The additional tests desired must be indicated on the electronic request or batch sheet that accompanies the specimen. No analysis or interpretation of results is performed.

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Cultured tumor cells can be used for a wide range of laboratory tests. Prior to testing, the tumor tissue will be cultured to obtain viable cells for genetic testing.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Not applicable

Interpretation Provides information to assist in interpretation of the test results

Once confluent flasks are established, the tumor cell cultures are sent to other laboratories, either within Mayo Clinic or to external sites, based on the specific testing requested.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Interfering factors:

-Lack of viable cells

-Bacterial contamination

-Cell death due to failure to transport tissue in an appropriate media

-Excessive transport time

-Exposure of the specimen to temperature extremes (freezing or >30 degrees C)

-Specimen has been stored or treated with formalin or another fixative or is paraffin-embedded

Clinical Reference Recommendations for in-depth reading of a clinical nature

Nelson M: Cytogenetic methods and findings in human solid tumors. In: Arsham MS, Barch MJ, Lawce HJ, eds. The AGT Cytogenetics Laboratory Manual. 4th ed. John Wiley and Sons, Inc; 2017:579-587

Special Instructions Library of PDFs including pertinent information and forms related to the test