TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: CHIDB    
Chimerism-Donor, Varies

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Complete chimerism analysis requires 3 specimens for 3 separate tests listed below. These specimens should be submitted when collected. An interpretive report will be provided once all specimens are received.

-CHRGB / Chimerism-Recipient Germline (Pretransplant), Varies

-CHIDB / Chimerism-Donor, Varies

-CHIMU / Chimerism Transplant No Cell Sort, Varies or CHIMS / Chimerism Transplant Sorted Cells, Varies

 

Billing occurs with the following tests:

-CHRGB / Chimerism-Recipient Germline (Pretransplant), Varies; for pre-transplant and donor specimens

-CHIMU / Chimerism Transplant No Cell Sort, Varies; for unsorted post-transplant specimens

-SORT1 / Chimerism Cell Sort 1 (Bill Only) and/or SORT2 / Chimerism Cell Sort 2 (Bill Only); for sorted post-transplant specimens. ordered under CHIMS / Chimerism Transplant Sorted Cells, Varies

 

If an additional donor specimen is submitted, ADONO / Additional Chimerism Donor (Bill Only) will be performed at an additional charge.

 

See Chimerism-Recipient Germline Testing Algorithm in Special Instructions.

Specimen Type Describes the specimen type validated for testing

Varies

Ordering Guidance

This test is for the pre-bone marrow transplant evaluation of the donor specimen.

Additional Testing Requirements

In addition to this test, complete chimerism analysis also requires specimen submission for the following:

-CHRGB / Chimerism-Recipient Germline (Pretransplant)

-CHIMU / Chimerism Transplant No Cell Sort, Varies or CHIMS / Chimerism Transplant Sorted Cells, Varies

These tests must be ordered on both the pre- and post-specimens under separate order numbers. The 3 specimens do not need to be submitted at the same time.

Shipping Instructions

1. Specimen must arrive within 7 days of collection.

2. Collect and package specimen as close to shipping time as possible.

Necessary Information

The following information is required:

1. Pertinent clinical history

2. Specimen source

3. Donor identifier and donor date of birth

4. Donor date of collection

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Submit only 1 of the following specimens:

 

Specimen Type: Blood

Container/Tube:

Preferred: Lavender top (EDTA)

Acceptable: Yellow top (ACD)

Specimen Volume: 6 mL

Collection Instructions:

1. Invert several times to mix blood.

2. Send specimen in original tube. Do not aliquot.

3. Label specimen as blood.

 

Specimen Type: Bone marrow

Container/Tube:

Preferred: Lavender top (EDTA)

Acceptable: Yellow top (ACD)

Specimen Volume: 2 mL

Collection Instructions:

1. Invert several times to mix bone marrow.

2. Send specimen in original tube. Do not aliquot.

3. Label specimen as bone marrow.

 

Specimen Type: Buccal swab

Supplies: Buccal Swab Kit (T543)

Container/Tube: Buccal smear collection kit

Specimen Volume: 2 Cyto-Pak brushes-1 per cheek

Collection Instructions:

1. Patient should rinse out mouth vigorously with mouthwash for approximately 15 seconds.

2. Remove Cyto-Pak brush from container only touching "stick" end. Save container.

3. Using medium pressure, rotate brush several times on inside of cheek.

4. Return brush to container and cap.

5. Repeat steps 2 through 4 on other cheek using second brush.

6. It is important that patient's buccal cells are not contaminated with cells from any other source. Do not touch bristles. Do not brush too vigorously. If blood appears, discard brush and restart collection process.

7. Label each container with patient's name and order number or hospital/clinic number.

Additional Information: It is important that the cells do not dry out during shipping. Ensure that container is tightly sealed.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Forms

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

Blood: 3 mL
Bone Marrow: 2 mL
Lesser volumes may be acceptable, depending on white cell count.
Call 800-533-1710 or 507-266-5700 with questions.

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Gross hemolysis Reject
Moderately to severely clotted Reject

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
VariesAmbient (preferred)7 days
 Refrigerated 7 days