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21OH - Overview: 21-Hydroxylase Antibodies, Serum

Investigating adrenal insufficiency Aiding in the detection of those at risk of developing autoimmune adrenal failure in the future

VLTU - Overview: Volatile Screen, Random, Urine

Detecting the presence of acetone, methanol, isopropanol, or ethanol in urine with subsequent quantitation

DLAC - Overview: D-Lactate, Plasma

As an adjunct to urine D-lactate (preferred) for the diagnosis of D-lactate acidosis

DLAU - Overview: D-Lactate, Urine

Preferred test for diagnosing D-lactate acidosis, especially in patients with jejunoileal bypass and short-bowel syndrome

NCDTS - Overview: Neurochondrin Antibody, Tissue Immunofluorescence Titer, Serum

Detecting neurochondrin-IgG in serum from patients presenting with cerebellar and brainstem syndrome Reporting an end titer result from serum specimens

NCDTC - Overview: Neurochondrin Antibody, Tissue Immunofluorescence Titer, Spinal Fluid

Detecting neurochondrin-IgG in spinal fluid (CSF) from patients presenting with cerebellar and brainstem syndrome Reporting an end titer result from CSF specimens

PDEIC - Overview: Phosphodiesterase 10A (PDE10A) IgG, Tissue Immunofluorescence, Spinal Fluid

Detecting phosphodiesterase 10A (PDE10A)-IgG in cerebrospinal fluid specimens Evaluation of autoimmune/paraneoplastic neurological syndromes among patients presenting with movement disorders and encephalopathy

PDEIS - Overview: Phosphodiesterase 10A (PDE10A) IgG, Tissue Immunofluorescence, Serum

Detecting phosphodiesterase 10A (PDE10A)-IgG in serum specimens Evaluation of autoimmune/paraneoplastic neurological syndromes among patients presenting with movement disorders and encephalopathy

PDETS - Overview: Phosphodiesterase 10A (PDE10A) IgG, Tissue Immunofluorescence Titer, Serum

Reporting an end titer result from phosphodiesterase 10A (PDE10A) in serum specimens Evaluation of autoimmune/paraneoplastic neurological syndromes among patients presenting with movement disorders and encephalopathy

FLEC - Overview: Flecainide, Serum

Optimizing flecainide dosage Assessing flecainide toxicity Monitoring compliance

MEX - Overview: Mexiletine, Serum

Assessing achievement of optimal therapeutic mexiletine concentrations Assessing potential mexiletine toxicity

LEVE - Overview: Levetiracetam, Serum

Monitoring serum concentration of levetiracetam, particularly in patients with kidney disease Assessing compliance with levetiracetam therapy Assessing potential toxicity of levetiracetam

FELBA - Overview: Felbamate (Felbatol), Serum

Determining whether a poor therapeutic response is attributable to noncompliance or lack of drug effectiveness Monitoring changes in serum concentrations resulting from interactions with coadministered drugs such as barbiturates and...

PDETC - Overview: Phosphodiesterase 10A (PDE10A) IgG, Tissue Immunofluorescence Titer, Spinal Fluid

Reporting an end titer result from phosphodiesterase 10A (PDE10A) in spinal fluid specimens Evaluation of autoimmune/paraneoplastic neurological syndromes among patients presenting with movement disorders and encephalopathy

SP5TC - Overview: Septin-5 Antibody, Tissue Immunofluorescence, Spinal Fluid

Detecting septin-5 IgG in spinal fluid (CSF) specimens Reporting an end titer result from CSF specimens

SP7TC - Overview: Septin-7 Antibody, Tissue Immunofluorescence Titer, Spinal Fluid

Detecting septin-7 IgG in cerebrospinal fluid (CSF) specimens Reporting an end titer result from CSF specimens

VORI - Overview: Voriconazole, Serum

Monitoring trough levels of voriconazole suggested for: -Individuals with reduced liver function -Individuals with cytochrome P450 (CYP) 2C19 alterations associated with poor metabolic function -Patients taking other medications that affect...

PFN - Overview: Propafenone, Serum

Monitoring propafenone therapy Assessing potential propafenone toxicity

MTXSG - Overview: Methotrexate Post Glucarpidase, Serum

Monitoring methotrexate concentrations post-glucarpidase therapy Documenting failure to respond that may be due to noncompliance Guiding dosage adjustments in patients with kidney failure

A1AF - Overview: Alpha-1-Antitrypsin, Random, Feces

Diagnosing protein-losing enteropathies, especially when used in conjunction with serum alpha-1-antitrypsin (AAT) levels as a part of AAT clearance studies

UREDF - Overview: Reducing Substance, Feces

Assisting in the differentiation between osmotic and nonosmotic diarrhea Screening test for: -Diarrhea from disaccharidase deficiencies, (eg, lactase deficiency) -Monosaccharide malabsorption

AHUGP - Overview: Atypical Hemolytic Uremic Syndrome (aHUS)/Thrombotic Microangiopathy (TMA) /Complement 3 Glomerulopathy (C3G) Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of atypical hemolytic uremic syndrome (aHUS), thrombotic microangiopathy (TMA), or complement 3 glomerulopathy (C3G) Establishing a diagnosis of...

ADEVL - Overview: Alzheimer Disease Evaluation, Spinal Fluid

Assessment of adults with cognitive impairment being evaluated for Alzheimer disease and other causes of cognitive impairment These assays should not be used to predict the development of dementia or other neurologic conditions or to...

CSMHU - Overview: Controlled Substance Monitoring Hybrid Drug Profile, 20 Drug Classes, High-Resolution Mass Spectrometry and Immunoassay Screen, Random, Urine

Detecting drug use involving stimulants, barbiturate, benzodiazepines, cocaine, opioids, and tetrahydrocannabinol This test is not intended for use in employment-related testing.

DYS2 - Overview: Dysautonomia, Autoimmune/Paraneoplastic Evaluation, Serum

Investigating idiopathic dysautonomic symptoms Directing a focused search for cancer in patients with idiopathic dysautonomia Investigating autonomic symptoms that appear in the course or wake of cancer therapy and are not explainable by...

CDGGP - Overview: Congenital Disorders of Glycosylation Gene Panel, Varies

Establishing a molecular diagnosis for patients with congenital disorders of glycosylation Identifying variants within genes known to be associated with congenital disorders of glycosylation, allowing for predictive testing of at-risk...

CDGF - Overview: Celiac Disease Gluten-Free Cascade, Serum and Whole Blood

Evaluating patients suspected of having celiac disease who are currently (or were recently) on a gluten-free diet

CDSP - Overview: Celiac Disease Serology Cascade, Serum

Evaluating patients suspected of having celiac disease, including patients with compatible symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disease, positivity...

PNEFS - Overview: Neuroimmunology Antibody Follow-up, Serum

Monitoring patients who have previously tested positive for one or more antibodies within the past 5 years in a Mayo Clinic Laboratories serum evaluation

ADNAS - Overview: Anti-DNase B Titer, Serum

Demonstration of acute or recent streptococcal infection using anti-DNase B titer

ADMA - Overview: Asymmetric Dimethylarginine, Plasma

Assessing the likelihood of future coronary events in patients with coronary heart disease, type II diabetes mellitus, or kidney disease Prompting intervention and assessing improvements among subjects with elevated ADMA and...

AKC - Overview: Adenylate Kinase Enzyme Activity, Blood

Assessment of adenylate kinase activity as part of the evaluation of chronic nonspherocytic hemolytic anemia

A_CR - Overview: Albumin/Creatinine Ratio

Calculating the albumin concentration per creatinine Assessing the potential for early onset of nephropathy in diabetic patients using random urine specimens

APTTP - Overview: Activated Partial Thromboplastin Time, Plasma

Monitoring heparin therapy (unfractionated heparin) Screening for certain coagulation factor deficiencies Detection of coagulation inhibitors such as lupus anticoagulant, specific factor inhibitors, and nonspecific inhibitors

AMPHU - Overview: Amphetamines Confirmation, Random, Urine

Confirming drug exposure involving amphetamines such as amphetamine and methamphetamine, phentermine, pseudoephedrine/ephedrine, methylenedioxyamphetamine (MDA), and methylenedioxymethamphetamine (MDMA)

ADLTX - Overview: Adulterants Survey, Chain of Custody, Random, Urine

Assess the possible adulteration of a urine specimen submitted for drug of abuse testing Providing the urine creatinine concentration for normalization purposes Chain of custody is required whenever the results of testing could be used...

ALPI - Overview: Alkaline Phosphatase Isoenzymes, Serum

Aid in the diagnosis and treatment of liver, bone, intestinal, and parathyroid diseases Determining the tissue source of increased alkaline phosphatase (ALP) activity in serum Differentiating between liver and bone sources of elevated...

AC1Q - Overview: Anti-C1q Antibodies, IgG, Serum

Evaluating patients with suspected anti-C1q vasculitis Predicting renal involvement in patients with systemic lupus erythematosus Detection of anti-C1q antibodies in serum

AHPRU - Overview: Antihypertension Panel, Random, Urine

Aid in the management of hypertension, especially treatment resistant hypertension Monitoring compliance in individuals prescribed antihypertensive drug therapy As a screen for to detect nonprescribed use of common diuretics

ASYNC - Overview: Alpha-Synuclein Protein Aggregates, Spinal Fluid

Detection of pathogenic alpha-synuclein (alpha-synuclein aggregates) in adult patients being assessed for clinically uncertain cognitive decline or clinically uncertain parkinsonian syndromes

AMTRP - Overview: Amitriptyline and Nortriptyline, Serum

Monitoring amitriptyline and nortriptyline serum concentrations during therapy Evaluating potential amitriptyline and nortriptyline toxicity May aid in evaluating patient compliance

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